Stress and anxiety are associated with nutritional deficiencies, which are thought to compound anxiety and stress. Biochemical evidence indicates that nutrients play a critically important role in central nervous system functioning. In addition, subclinical nutrient deficiencies may influence psychological wellbeing and potentially precede physical or emotional/affective disorders. Chronic stress leads to a cascade of negative physical and mental challenges such as cardiovascular disease, lifestyle-related diabetes, metabolic and immune dysfunction, along with cognitive decline and depression.